Dataset for the project "Inflammation and depression: a multidisciplinary approach to dissect pathogenetic mechanisms in the onset, comorbidity, and treatment response" - PNRR-MAD-2022-12375859

Dataset for the project “Inflammation and depression: a multidisciplinary approach to dissect pathogenetic mechanisms in the onset, comorbidity, and treatment response” - PNRR-MAD-2022-12375859 The present folder contains the following files specific to UO1: Related to AIM 1: Depressed_RNAseq_rawcounts.xlsx Metadata_invitro.xlsx: description of the samples in the file In vitro_filteredcounts.xlsx In vitro_filteredcounts.xlsx Related to AIM 2: Biochemical_PNRR.xlsx: protein levels of cytokines Pharmacokinetics_PNRR.xlsx: drug concentrations in blood for antidepressants TGS_INDEL_PNRR.xlsx: target gene sequencing results for insertions/deletions TGS_SNP_PNRR.xlsx: target gene sequencing results for SNPs Users must clarify how they intend to use data here uploaded and whether the research protocol has been approved by an Ethics committee. Data on unpublished results will be available, under the same restrictions, after publication本数据集隶属于项目“炎症与抑郁：解析发病、共病及治疗应答中致病机制的多学科研究方法（Inflammation and depression: a multidisciplinary approach to dissect pathogenetic mechanisms in the onset, comorbidity, and treatment response）”——编号PNRR-MAD-2022-12375859 本文件夹包含以下针对UO1的专属文件： 针对研究目标1（AIM 1）的文件如下： Depressed_RNAseq_rawcounts.xlsx Metadata_invitro.xlsx：用于说明In vitro_filteredcounts.xlsx中样本的相关信息 In vitro_filteredcounts.xlsx 针对研究目标2（AIM 2）的文件如下： Biochemical_PNRR.xlsx：细胞因子蛋白水平数据 Pharmacokinetics_PNRR.xlsx：抗抑郁药物血液药物浓度数据 TGS_INDEL_PNRR.xlsx：插入/缺失变异目标基因测序结果 TGS_SNP_PNRR.xlsx：单核苷酸多态性（SNP）目标基因测序结果 使用者需明确说明其对本上传数据的使用意图，且需确认研究方案已获得伦理委员会批准。未发表的研究结果数据将在发表后，遵循相同限制条款开放获取。