Dysbiosis and associated stool features improve prediction of response to biological therapy in inflammatory bowel disease

Prospective study investigating the potential associations between gut microbiota composition and the outcome of biological therapies in patients with active IBD (203 Crohn's disease, 93 ulcerative colitis). Quantitative microbiome profiles of pre- and post-treatment faecal samples were obtained combining flow cytometry with 16S rRNA gene amplicon ?amplicon sequencing.