NeuroQOL Clinical Validation Study (aka Wave II)

From January 15, 2009 to January 30, 2010 Wave II short form testing in clinical samples was conducted to increase the sample size for some of the instrument calibration analyses and to conduct validation studies. Wave II participants were recruited from Cleveland Clinic Foundation, Dartmouth-Hitchcock Medical Center, NorthShore University HealthSystem, Northwestern University Feinberg School of Medicine, Rehabilitation Institute of Chicago, University of Chicago, University of Puerto Rico, and the University of Texas Health Science Center. Validation results will be discussed in subsequent publications. The sampling plan facilitated obtaining item calibrations for the different domain areas, estimating profile scores for varied subgroups, confirming factor structure, and conducting item and bank analyses. Given the large number of items (>500), we knew that participants could not be asked to respond to the full item pool. It was estimated that participants would respond to four questions per minute, with the maximum number of items administered for each respondent approximately 150.