Source data for the C-GWAS study of human facial shape

These dataset are from Xiong et al. Combined genome-wide association study of facial traits in Europeans increases explained variance and improves prediction. Nat Commun. 2025 upcoming. This dataset contains meta-analysis GWAS summary statistics of 946 pairwise distances between 44 facial landmarks from 5 cohorts of European ancestry. The summary statistics consist of a unified SNP information file (filename SnpInfo.tsv) and 946 separate data files containing the Beta and P for each distance (filename X_Y.tsv, where X and Y represent the two landmarks of the distance). The 946 data files are grouped into 36 folders, indicating that they are distances within (n=8) or between (n=28, pairwise) 8 facial regions. The definitions of landmarks and facial regions can be found in Figure 1 of the manuscript.本数据集源自Xiong等人的研究：《欧洲人群面部特征全基因组关联研究的整合分析提升解释方差与预测性能》，该研究将于2025年在《自然通讯》（Nature Communications）刊出。本数据集包含来自5个欧洲血统队列的44个面部标志点（facial landmarks）间946组成对距离的荟萃分析全基因组关联研究（Genome-Wide Association Study, GWAS）汇总统计数据。该汇总统计数据包含一个统一的单核苷酸多态性（Single Nucleotide Polymorphism, SNP）信息文件（文件名为SnpInfo.tsv），以及946个独立的数据文件：每个文件存储了对应一组距离的效应量Beta与显著性P值，文件命名格式为X_Y.tsv，其中X与Y分别代表该距离对应的两个面部标志点。这946个数据文件被划分为36个文件夹，其中8个文件夹对应单个面部区域内部的距离计算，剩余28个文件夹对应8个面部区域之间的成对距离计算。面部标志点与面部区域的定义可参见该研究论文的图1。