Roles of Runx2 in chromatin landscape in skeletal development
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This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
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2022-12-09
相关数据集
Roles of Runx2 in chromatin landscape in skeletal development [ChIP-Seq, ATAC-Seq]
The transcriptional regulator Runx2 has essential roles in chondrocytes and osteoblasts, central to the coordinated development of cartilage and bone. However, the regulatory mechanisms underlying Run
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Histone H3 Lysine 27 methylation Regulates Skeletal Growth by Suppressing Wnt and TGF-Ã Signaling
Polycomb repressive complex 2 (PRC2) controls maintenance and lineage determination of stem cells by suppressing genes that regulate cellular differentiation and tissue development. However, the role
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Epigenetic Control of Skeletal Development by the Histone Methyltransferase Ezh2
Inhibition of H3K27 methyltransferase EZH2 enhances osteogenic commitment of human mesenchymal progenitors and Ezh2 inactivation in mouse calvarial cells induces a post-proliferative state concomitant
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Histone H3 Lysine 27 methylation Regulates Skeletal Growth by Suppressing Wnt and TGF-β Signaling
Polycomb repressive complex 2 (PRC2) controls maintenance and lineage determination of stem cells by suppressing genes that regulate cellular differentiation and tissue development. However, the role
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Gene expression profiles with WT and Tet KO osteoblasts. Gene expression profiles with WT and Tet KO osteoblasts
The Ten-eleven translocation (TET) family of dioxygenases can mediate cytosine demethylation by catalyzing the oxidation of 5-methylcytosine (5mC). TET-mediated DNA demethylation controls the proper d
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