In urodele amphibians, limb regeneration involves the dedifferentiation of muscle myotubes into single cells that may acquire pluripotent potential. We have employed small molecules (myoseverin and BI

NIAID Data Ecosystem50

Direct Reprogramming of Non-limb Fibroblasts to Cells with Properties of Limb Progenitors

细胞重编程

肢体再生

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

NIAID Data Ecosystem50

Direct reprogramming of mouse fibroblasts into functional skeletal muscle progenitors. Mus musculus

细胞重编程

骨骼肌细胞

Skeletal muscle harbors quiescent stem cells termed satellite cells and proliferative progenitors termed myoblasts, which play pivotal roles during muscle regeneration. However, current technology doe

NIAID Data Ecosystem50

Chemical-based external stimulation reprograms BJs into FiNs

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