Correlation between PML-NBs or centromeres HSV-1 genome association and LAT expression.
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To evaluate the impact of HSV-1 genome association with PML-NB (left) and centromeres (right), on LAT expression, LAT RNA and HSV-1 association with PML-NB or centromere was determined in individual neurons displaying multiple pattern of HSV-1 genome, using an immuno-RNA/DNA-FISH approach. The proportion of neurons in which an association of at least one HSV-1 spot and either PML or centromeres was determined in LAT+ and LAT− neurons. The values are in percentage of the total infected neurons within an entire TG of one latently infected mouse.
创建时间：
2015-12-02
