Al Moussawi et al 2022 "Mutant Ras and inflammation-driven skin tumorigenesis is suppressed via a JNK-iASPP-AP1 axis"

Raw imaging data that was used to generate the figures for Al Moussawi et al 2022 "Mutant Ras and inflammation-driven skin tumorigenesis is suppressed via a JNK-iASPP-AP1 axis". Please refer to the paper in Cell Reports for more explanation. The sequencing data generated during this study is available at GEO under SuperSeries GSE188448. Code to reproduce this analysis can be found at github.com/tcarroll/iASPP_keratinocyte_ChIPseq_RNAseq. A publicly accessible UCSC genome browser session to assist visualization of ChIP-seq results from this study is available at http://genome.ucsc.edu/s/CarrollTM/iASPP_keratinocyte_p63.

本数据集为生成Al Moussawi等人2022年发表于《Cell Reports》的论文《Mutant Ras and inflammation-driven skin tumorigenesis is suppressed via a JNK-iASPP-AP1 axis》（中文译题：突变型Ras与炎症驱动的皮肤肿瘤发生可通过JNK-iASPP-AP1轴实现抑制）中所有图表所用的原始成像数据。详细阐释请参阅该论文原文。本研究产生的测序数据可于基因表达综合数据库（Gene Expression Omnibus, GEO）的超级系列数据集GSE188448中获取。可用于复现本分析的代码已上传至github.com/tcarroll/iASPP_keratinocyte_ChIPseq_RNAseq。本研究的染色质免疫沉淀测序（Chromatin Immunoprecipitation Sequencing, ChIP-seq）结果可通过公开可访问的UCSC基因组浏览器（UCSC Genome Browser）会话进行可视化查看，会话链接为http://genome.ucsc.edu/s/CarrollTM/iASPP_keratinocyte_p63。