YFV CRISPR screening

NIAID Data Ecosystem2026-05-02 收录

病毒受体发现

CRISPR功能性筛选

数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP606330 数据链接链接失效反馈

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资源简介：

This CRISPR screen is to identify receptors for Yellow Fever virus. We chose a customized human library targeting only plasma membrane.

创建时间：

2025-08-05

Surfaceome CRISPR screen to identify cellular receptors for SARS-CoV-2 spike protein

病毒受体发现

CRISPRi筛选

We performed the surfaceome CRISPR activation screen in human melanoma A375 cell line to identify human surface proteins that regulate SARS-CoV-2 spike binding to cells.

NIAID Data Ecosystem40

CRISPR-Cas9 screens to identify regulators of differentiation in Toxoplasma gondii. CRISPR-Cas9 screens to identify regulators of differentiation in Toxoplasma gondii

弓形虫分化

CRISPR功能性筛选

Targeted gRNA screen against putative nucleic-acid binding proteins in a differentiation reporter strain context. By looking for gRNAs enriched in parasites no longer able to activate reporter express

NIAID Data Ecosystem40

Multi-virus CRISPR screening data in VeroE6 cells. Multi-virus CRISPR screening data in VeroE6 cells

CRISPR功能性筛选

宿主因子鉴定

We report the results of CRISPR survival screens in the context of multiple viral infections. Two sgRNA pools were used: one targeting the SARS-CoV-2 RNA interactome proteins, and one targeting mitoch

NIAID Data Ecosystem30

Table S3 from CBF-Beta Mitigates PI3K-Alpha–Specific Inhibitor Killing through PIM1 in PIK3CA -Mutant Gastric Cancer

CRISPR功能性筛选

药物敏感性

Beta scores generated for DMSO and BYL719 treated populations using MAGeCK analysis pipeline

NIAID Data Ecosystem40

Genome-scale CRISPR-Cas9 knockout screens for enterovirus D68 and rhinovirus C15

CRISPR功能性筛选

宿主因子鉴定

H1-HeLa cells were stably transduced with lentiCas9-Blast (Addgene, Plasmid #52962) and subsequently selected using blasticidin to generate constitutively expressing Cas9 H1-HeLa cells. A single Cas9-

NIAID Data Ecosystem40

YFV CRISPR screening

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