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Synthesis of (2<i>S</i>)‑2-Chloro-2-fluororibolactone via Stereoselective Electrophilic Fluorination

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NIAID Data Ecosystem2026-03-10 收录
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A novel and efficient route for the preparation of (2S)-2-chloro-2-fluorolactone 29 is described. This approach takes advantage of a highly efficient diastereoselective electrophilic fluorination reaction (94% yield; >50:1 dr)

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2017-12-01
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