Median overall survival and progression-free survival hazard ratios (HRs) and 95% Credible Intervals for cabazitaxel, abiraterone and enzalutamide using Bayesian fixed effects modeling.
1Multiplicity by Mann-Whitney test. Control≠Drug : P = 0.0387.2Fisher exact test Grades 3 vs 4, Control≠Drug : P = 0.0341.3Fisher exact test Grades 3 vs 4, Control≠Drug : P = 0.0302.
A novel structural series of quinoline derivatives were designed, synthesized and biologically evaluated as PI3K/mTOR dual inhibitors upon incorporation of C-4 acrylamide fragment. Consequently, all o
