We sequenced CTCF binding sites in Akt1+/+ or Akt1-/- mouse embryonic fibroblast (MEF) cell line. Overall design: The information of CTCF binding sites in wildtype (WT) and Akt1-/- MEF cells was gener
ChIPmentation-seq analysis of CTCF and RAD21 in wildtype and mutant CTCF binding sites alleles ChIPmentation-seq analysis of CTCF and RAD21 in wildtype and mutant CTCF binding sites alleles
Our studies have revealed that a large class of CTCF binding sites – namely the upstream sites – conform neither to a conformational nor a local recombinase activating role. Their conserved spatial di
UPF-1-UPF-2-UPF-3 complex-orchestrated nonsense-mediated mRNA decay (NMD) is a well-characterized eukaryotic cellular surveillance mechanism that not only degrades aberrant transcripts to protect the