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Data from: A novel loss of function Melanocortin-4-Receptor mutation (MC4R-F313Sfs*29) in morbid obesity

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肥胖遗传学

MC4R受体功能

数据链接：

https://figshare.com/articles/dataset/RAW_DATA_xlsx/13187711 数据链接链接失效反馈

官方服务：

资源简介：

Raw data of FRET-based cAMP measurements in HEK293 cells expressing MC4R

应用场景：

创建时间：

2020-11-04

全基因组关联分析

肥胖遗传学

BackgroundThirty-two common variants associated with body mass index (BMI) have been identified in genome-wide association studies, explaining ∼1.45% of BMI variation in general population cohorts. We

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Top SNP per region for all GOYA hits p −5 in either the overweight/control dichotomous analysis or the quantitative BMI linear regression ananlysis.

肥胖遗传学

基因组关联分析

*regions with previous evidence for association with obesity. **genome-wide significant p<5×10−8. §only the sign (+/−) of the beta coefficients are shown for the BMI linear regression analysis, as the

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Table3_Genetic association-based functional analysis detects HOGA1 as a potential gene involved in fat accumulation.XLSX

肥胖遗传学

脂肪代谢调控

Although there are a number of discoveries from genome-wide association studies (GWAS) for obesity, it has not been successful in linking GWAS results to biology. We sought to discover causal genes fo

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Association between rs939347 and the risk of obesity by gender.

肥胖遗传学

性别差异分析

Obese is defined as having a BMI>30 kg/m2. Lean is defined as having a BMI<26 kg/m2. Abbreviations: CI, confidence interval; OR, odds ratio.

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Additional file 16 of Disentangling the genetic overlap between ischemic stroke and obesity

缺血性中风遗传关联

肥胖遗传学

Additional file 16.

Figshare2024-12-30 更新50