Supplementary Material for: Assessment of Social Cognition and Theory of Mind: Initial Validation of the Geneva Social Cognition Scale

<b><i>Background:</i></b> Social cognition is widely studied in neurology. At present, such evaluations are designed for research or for specific diseases and simple general clinical tools are lacking. We propose a clinical evaluation tool for social cognition, the Geneva Social Cognition Scale (GeSoCS). <b><i>Methods:</i></b> The GeSoCS is a 100-point scale composed of 6 subtests (theory of mind stories, recognition of social emotions, false beliefs, inferences, absurdity judgement and planning abilities) chosen from different validated tests of social and cognitive evaluation. Eighty-four patients with neurological disorders and 52 controls participated in the study. Evaluation duration lasted 20-60 min. <b><i>Results:</i></b> Mean scores were 92.6 ± 4.5 for controls and 76.5 ± 15.3 for patients and differentiate patients and controls in all subtests. With a cut-off score of 84, the scale had a sensitivity of 62% and a specificity of 94%. In our stroke subgroup, right CVAs failed in cartoons, inferences, ‘mind in the eyes', and in the temporal rule task while left CVAs were impaired in verbal/discourse tasks (social cognition, inferences, absurd stories, and cartoons. <b><i>Conclusions:</i></b> The GeSoCS is a medium duration assessment tool that appears to detect and characterize significant social impairment in neurological patients.

<b><i>背景：</i></b> 社会认知在神经病学领域受到广泛研究。当前，此类评估工具多为特定研究或针对单一疾病开发，缺乏通用简便的临床评估工具。本研究提出一款面向社会认知的临床评估工具——日内瓦社会认知量表（Geneva Social Cognition Scale, GeSoCS）。
<b><i>方法：</i></b> 该量表总分为100分，包含6个分测验，分别为心理理论（theory of mind）故事测验、社会情绪识别测验、错误信念测验、推理测验、荒谬判断测验以及计划能力测验，所有分测验均选自已通过效度验证的社会与认知评估工具。本研究共纳入84例神经系统疾病患者与52名健康对照，评估时长为20至60分钟。
<b><i>结果：</i></b> 健康对照的平均得分为92.6±4.5，神经系统疾病患者的平均得分为76.5±15.3，且各分测验均可有效区分患者与健康对照。当截断值设定为84分时，该量表的灵敏度为62%，特异度为94%。在卒中亚组分析中，右侧脑血管意外（cerebrovascular accidents, CVA）患者在卡通图片测验、推理测验、“眼神读心（mind in the eyes）”测验以及时间规则任务中表现受损；而左侧脑血管意外患者则在言语/话语任务（包括社会认知、推理、荒谬故事及卡通图片测验）中存在功能缺损。
<b><i>结论：</i></b> 日内瓦社会认知量表是一款耗时适中的评估工具，可有效检测并精准刻画神经系统疾病患者的显著社会认知缺损特征。