Replication Data for: Promoting Chemotherapy Sensitivity in Glioblastoma: The Therapeutic Role of Succisa Pratensis in the modulation of Pregnane X receptor Activity

This dataverse include the Tandem mass tag LC-MS/MS proteomics dataset of changed proteins generated in the study: “Promoting Chemotherapy Sensitivity in Glioblastoma: The Therapeutic Role of Succisa Pratensis in the modulation of Pregnane X receptor Activity” by Francesca Servidio, Fabio Pirovano, Sofia Remedia, Chiara Pellizzer, Martina Nespoli, Bruno Galuzzi, Marcella Bonanomi, Sara Mallia, Mauro Commisso, Flavia Guzzo, Clarissa Gervasoni, Daniela Gaglio, Manuela Moriggi, Daniele Capitanio, Gloria Bertoli, Alessandro Giammona and Alessia Lo Dico.
Data were generated by LC-ESI-MS/MS with TMT isobaric labeling quantitation. Mass spectra generated on a orbitrap Fusion tribrid mass spectrometer (Thermo) were analyzed using MaxQuant software (Max-Planck-Institute of Biochemistry, Munich, Germany, version 1.6.17.0). Statistical analyses were performed using the Perseus software (Max Planck Institute of Biochemistry, Munich, Germany, version 2.0.11). For statistical analysis, ANOVA test and Tukey's multicomparison analysis with a p-value threshold of 0.05 were applied. To exclude the presence of false positives from the analysis, Benjamini–Hochberg false discovery rate test was applied.