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Synaptic Scaling of Corticostriatal Circuits Underlies Hyperactivity in GABA Transporter-1 Deficient Mice

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To explore the potential mediators of corticostriatal synaptic scaling in GAT1-/- mice, whole-tissue mRNA sequencing was carried out for the dorsal striatum of GAT1+/+ and GAT1-/- mice. Comparative gene expression profiling analysis of RNA-seq data for striatum of GAT1 wild type and its knockout mice (GAT1+/+ and GAT1-/- mice).

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