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A RAB5/RAB4 recycling circuitry induces a proteolytic invasive program and promotes tumor dissemination

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NIAID Data Ecosystem2026-03-10 收录
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https://www.omicsdi.org/dataset/bioimages/S-JCBD-201403127
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Doxycycline-inducible RAB5AS34N-expressing MDA-MB-231 cells were injected into the mammary fat pads of NOD SCID/IL2Rgamma null (NSG) mice. Three weeks after injection, mice were fed with doxycyline to induce transgene expression. Primary tumors were allowed to develop for 4–6 weeks before removal by mastectomy. Metastases were analyzed 4 weeks after removal of the primary tumor.
创建时间:
2018-11-29
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