Histone deacetylase 3 is essential for pregnancy. Mus musculus

HDAC3 is necessary for implantation and decidualization, and its defects that may be a cause of reproductive failure. We used microarrays to detail the mechanism underlying HDAC3 loss for reproductive failure Overall design: Uteri of Hdac3 f/f and Hdac3 d/d mice were selected at 6 weeks of age for RNA extraction and hybridization on Affymetrix microarrays.