Transcriptome-wide Profile of Cerebral Cavernous Malformations Patients Reveal Important Long noncoding RNA molecular signatures. Transcriptome-wide Profile of Cerebral Cavernous Malformations Patients Reveal Important Long noncoding RNA molecular signatures

In this study, by transcriptome-wide approach we demonstrate that lncRNAs are prevalent in CCMs disease and are likely to play critical roles in regulating important signaling pathways involved in the disease progression. We believe, that detailed future investigations on these set of identified lncRNAs can provide useful insights into the biology and, ultimately, in preventing this debilitating disease. Overall design: Next Generation Sequencing analyses of transcriptome profiles from CCM patients