Cobalt-Catalyzed Enantioselective Directed C–H Alkylation of Indole with Styrenes
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https://figshare.com/articles/dataset/Cobalt_Catalyzed_Enantioselective_Directed_C_H_Alkylation_of_Indole_with_Styrenes/2220061
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资源简介：
A cobalt–chiral
phosphoramidite catalyst promotes enantioselective imine-directed
C2-alkylation of Boc-protected indoles with styrenes. The reaction
affords 1,1-diarylethane products in moderate to good yields with
good enantioselectivities under mild conditions. A deuterium-labeling
experiment suggests that the enantioselectivity is controlled by both
the styrene insertion and the C–C reductive elimination steps.
创建时间：
2015-01-02
