WGCNA analysis in cHCs and endogenous HCs.

(A) Sample clustering was conducted to detect outliers. This analysis was based on the expression data of top 4000 variable genes in the total 251 cells with 161 Atoh1-HA+ cHCs and 90 SCs available in Yamashita et al [7] (S2 Table). Genes were clustered based on a dissimilarity measure. The branches correspond to modules of highly interconnected groups of genes. Colors in the horizontal bar represent the five cell types assigned by scRNA-seq analysis. (B) Selection of the soft-thresholding powers for scale-free co-expression network. The left panel showed the scale-free fit index versus soft-thresholding power. The right panel displayed the mean connectivity versus soft-thresholding power. Power 4 was used. (ZIP)