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Urinary Metabolomic Profile in Children with Autism Spectrum Disorder

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DataCite Commons2025-01-30 更新2025-04-17 收录
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Autism spectrum disorder (ASD) has been associated with disruptions in tryptophan (TRP) metabolism, affecting the production of key neuroactive metabolites. Investigating these metabolic pathways could yield valuable biomarkers for ASD severity and progression. We included 44 children with ASD and 44 healthy controls, members of the same family. ASD group average age was 10.7 years while control group was 9.4 years. Analysis of TRP metabolites in urine samples was performed using a ultra-high performance liquid chromatography (UHPLC) and tandem mass spectrometry (MS/MS) in selected reaction monitoring detection mode (SRM).
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Panorama Public
创建时间:
2024-12-12
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