Chromatin accessibility profiles of the mouse jejunum in a bidirectional nutrient supply model

The small intestine is the primary organ for nutrient sensing and absorption, in order to more comprehensively reveal the nutrient sensing and response of intestinal cells, we used ATAC sequencing to reveal the effects of enteral and serosal nutrients on the intestinal tract in a bidirectional nutrient supply mode. Overall design: Mice were treated with Control, BSF, DSF and LSF for 2 weeks, and jejunal epithelial cells were collected by flow sorting.