Transcriptional Profiles Induced by the Aryl Hydrocarbon Receptor Agonists 2,3,7,8-Tetrachlorodibenzo-p-dioxin, 2,3,7,8-Tetrachlorodibenzofuran and 2,3,4,7,8-Pentachlorodibenzofuran in Primary Rat Hepatocytes. Rattus norvegicus

Transcriptional profiling of primary rat hepatocytes exposed to high and low doses of three compounds, as well as untreated cells. All samples were co-hybridized with DMSO controls. Overall design: A direct two-color experiment design, with each treated sample co-hybridized with a DMSO control. Hepatocytes derived from two animals were used as biological replicates. Four microarrays were completed for each chemical/dose combination. The four replicate arrays represent two dye-swapped microarrays for each of the two animals.