Number of Tg mice expressing bioluminescence signals in pancreas and skin during pancreatic maturation against the number of tested mice.

Luciferase activity in the pancreas was detected by ex vivo imaging of upper 105 (p/s/cm2/sr) and in skin by in vivo imaging of upper 105 (p/s/cm2/sr) using the Xenogen IVIS Imaging System. The numbers of bioluminescence positive lines observed from the total tested are shown. Colored boxes represent a positive bioluminescence signal.