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Dataset for the spontaneous tail coiling (STC) of zebrafish embryos exposed to single neuroactive substances and their mixtures

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Zenodo2021-04-23 更新2026-05-25 收录
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The spontaneous tail coiling (STC) of zebrafish embryos represents the earliest observable motor activity in the developing neural network. We present here the STC data for single substances (singlechemicaldata) used for the concentration response curves which are published in the paper: "Optimization of the spontaneous tail coiling test for fast assessment of neurotoxic effects in the zebrafish embryo using an automated workflow in KNIME by Ogungbemi et al. 2020. In addition, we present STC data for chemical mixtures (mixturedata) which were used to generate the concentration response curves in the paper manuscript: "Assessing combined effects for mixtures of similar and dissimilar acting neuroactive substances on zebrafish embryo movement by Ogungbemi et al. 2021 For more details on the data, please see the papers.

斑马鱼胚胎的自发性尾部盘绕运动(spontaneous tail coiling, STC)是发育神经网络中最早可观测到的运动活动。我们在此提供了单一物质的STC数据(singlechemicaldata),该数据被用于构建Ogungbemi等人2020年发表的论文《使用KNIME自动化工作流快速评估斑马鱼胚胎神经毒性的自发性尾部盘绕运动测试方法优化》中的浓度响应曲线。此外,我们还提供了化学混合物的STC数据(mixturedata),该数据被用于生成Ogungbemi等人2021年的论文手稿《评估相似与不同作用模式的神经活性物质混合物对斑马鱼胚胎运动的联合效应》中的浓度响应曲线。如需了解该数据集的更多细节,请参阅上述两篇论文。

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Zenodo
创建时间:
2021-04-23
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