MRI characteristics and extent of tumor removal in cervical dumbbell-shaped schwannomas

Data of 72 patients who underwent surgical treatment for cervical dumbbell-shaped schwannomas were retrospectively reviewed. Tumor level (p = 0.009, Pearson’s chi-square test), VA involvement (p < 0.001, linear-by-linear association test), and SI on T2-weighted images (T2-WIs) (p = 0.006, Fisher’s exact test) were statistically significantly different between the GTR and STR groups. Univariate analysis demonstrated that upper level (odds ratio [OR] 4.00, 95% confidence interval [CI] 1.50-10.69; p = 0.006), pushed VA (OR 0.11, 95% CI 0.03-0.45; p = 0.002), encased VA (OR 0.02, 95% CI 0.01-0.14; p < 0.001), and Hyper-SI on T2-WI (OR 12.46, 95% CI 1.49-104.51; p = 0.020) were significant predictors for GTR.

本研究回顾性分析了72例接受手术治疗的颈椎哑铃型神经鞘瘤患者的临床资料。全切除术（Gross Total Resection, GTR）组与次全切除术（Subtotal Resection, STR）组在肿瘤累及节段（p=0.009，皮尔逊卡方检验）、椎动脉（Vertebral Artery, VA）受累情况（p<0.001，线性趋势卡方检验）以及T2加权成像（T2-WIs）上的信号强度（Signal Intensity, SI）（p=0.006，费舍尔精确检验）方面的差异均具有统计学意义。单因素分析结果显示，肿瘤累及上颈段（比值比[OR]=4.00，95%置信区间[CI]=1.50~10.69；p=0.006）、椎动脉受压移位（OR=0.11，95%CI=0.03~0.45；p=0.002）、椎动脉被肿瘤包裹（OR=0.02，95%CI=0.01~0.14；p<0.001）以及T2加权成像上呈高信号（OR=12.46，95%CI=1.49~104.51；p=0.020）均为影响全切除术完成的显著预测因素。