In vitro neutralization of lethality of Afro-Asian cobra and krait venoms by NPAV.

For LD50 and ED50, values in brackets are 95% CI.2.5 or 5.0 LD50 of venom in 50 µL was premixed with 200 µL of NPAV (Neuro Polyvalent Snake Antivenom) and incubated for 30 min. The mixture was then injected into mice (n = 4, 20–25 g) and monitored for 48 h. NE: Not effective at maximum volume of antivenom (200 µL) permitted.*: estimated value, as the maximum volume of antivenom (200 µL) only achieved 50% protection of the animals.