SUPPORTING MATERIAL FOR ARTICLE: Experimental Setup in Low Earth Orbit, Part 1- Analyzing the Impact of Space Conditions on Cannabinoid Composition Using Advanced MCE with HVS and C4D.

This document provides a brief description of the ‘Genesis of Mission Possible’ and details all preliminary runs conducted with the <i>Genoplant Analyzer (ER-510)</i>, focusing on detecting cannabinoids in standard and flower samples. Chromatograms are unedited, and peaks are not normalized. The study introduces an advanced MCE setup, utilizing high voltage sequencing (HVS) and capacitively coupled contactless conductivity detection (C4D), to evaluate the impact of space conditions on cannabinoid composition. The research extends beyond previous ISS experiments by analyzing samples returned from Earth orbit using the MayaSat-1 biological incubator aboard the Exploration Company’s Mission Possible spacecraft. By reducing separation times to 2 minutes for 15 cannabinoids, this study significantly enhances analysis speed and efficiency, demonstrating the potential of this approach for both space research and practical applications.