Crystal Structure of Renin with Inhibitor 8

Crystal Structure of Renin with Inhibitor 8 Descriptor: N-[(2S,4S,5S,7R)-4-AMINO-8-(BUTYLAMINO)-5-HYDROXY-7-METHYL-2-(1-METHYLETHYL)-8-OXOOCTYL]-2-(3-METHOXYPROPOXY)BENZAMIDE, RENIN Authors: Rahuel, J, Rasetti, V, Maibaum, J, Rueger, H, Goschke, R, Cohen, N.C, Stutz, S, Cumin, F, Fuhrer, W, Wood, J.M, Grutter, M.G. Deposit date: 2007-05-21 Release date: 2007-07-03 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Structure-Based Drug Design: The Discovery of Novel Nonpeptide Orally Active Inhibitors of Human Renin Chem.Biol., 7, 2000结合抑制剂8的肾素（Renin）晶体结构 描述符：N-[(2S,4S,5S,7R)-4-氨基-8-(丁基氨基)-5-羟基-7-甲基-2-(1-甲基乙基)-8-氧代辛基]-2-(3-甲氧基丙氧基)苯甲酰胺，靶标：肾素 作者：Rahuel J, Rasetti V, Maibaum J, Rueger H, Goschke R, Cohen N.C, Stutz S, Cumin F, Fuhrer W, Wood J.M, Grutter M.G 存档日期：2007-05-21 发布日期：2007-07-03 最后修改日期：2024-11-13 方法：X射线衍射（X-RAY DIFFRACTION，3.2埃（Å）） 引用文献：《基于结构的药物设计：新型非肽类口服活性人肾素抑制剂的发现》，《Chem.Biol.》，第7卷，2000年