Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with the Triaryl-substituted Imine Analog, 4-{(E)-(4-hydroxyphenyl)[(2-methylphenyl)imino]methyl}benzene-1,3-diol

Protein Data Bank Japan2023-09-27 更新2026-03-21 收录

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Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with the Triaryl-substituted Imine Analog, 4-{(E)-(4-hydroxyphenyl)[(2-methylphenyl)imino]methyl}benzene-1,3-diol Descriptor: 4-{(E)-(4-hydroxyphenyl)[(2-methylphenyl)imino]methyl}benzene-1,3-diol, Estrogen receptor, Nuclear receptor coactivator 2 Authors: Nwachukwu, J.C, Wright, N.J, Srinivasan, S, Zheng, Y, Wang, S, Min, J, Dong, C, Liao, Z, Cavett, V, Nowak, J, Houtman, R, Carlson, K.E, Josan, J.S, Elemento, O, Katzenellenbogen, J.A, Zhou, H.B, Nettles, K.W. Deposit date: 2015-09-22 Release date: 2016-05-04 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Predictive features of ligand-specific signaling through the estrogen receptor. Mol.Syst.Biol., 12, 2016

结合三芳基取代亚胺类似物4-{(E)-(4-羟基苯基)[(2-甲基苯基)亚氨基]甲基}苯-1,3-二醇的雌激素受体α（ER-alpha）配体结合域晶体结构描述项：4-{(E)-(4-羟基苯基)[(2-甲基苯基)亚氨基]甲基}苯-1,3-二醇、雌激素受体（Estrogen receptor）、核受体辅激活因子2（Nuclear receptor coactivator 2）作者：Nwachukwu, J.C, Wright, N.J, Srinivasan, S, Zheng, Y, Wang, S, Min, J, Dong, C, Liao, Z, Cavett, V, Nowak, J, Houtman, R, Carlson, K.E, Josan, J.S, Elemento, O, Katzenellenbogen, J.A, Zhou, H.B, Nettles, K.W. 沉积日期：2015-09-22 发布日期：2016-05-04 最后修改日期：2023-09-27 实验方法：X射线衍射（2.3埃）引用文献：《通过雌激素受体的配体特异性信号传导的预测特征》，Mol.Syst.Biol., 12, 2016

创建时间：

2015-09-22