Crystal structure of Thymidylate Synthase Complementing Protein (TM0449) from Thermotoga maritima with FdUMP at 2.1 A resolution

Crystal structure of Thymidylate Synthase Complementing Protein (TM0449) from Thermotoga maritima with FdUMP at 2.1 A resolution Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5-FLUORO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, TRIETHYLENE GLYCOL, ... Authors: Mathews, I.I, Deacon, A.M, Canaves, J.M, McMullan, D, Lesley, S.A, Agarwalla, S, Kuhn, P, Joint Center for Structural Genomics (JCSG) Deposit date: 2003-02-18 Release date: 2003-06-24 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Functional Analysis of Substrate and Cofactor Complex Structures of a Thymidylate Synthase-Complementing Protein Structure, 11, 2003

海栖热袍菌（Thermotoga maritima）来源的胸苷酸合酶互补蛋白（TM0449）与FdUMP共晶的晶体结构，分辨率为2.1 Å。描述信息：4-(2-羟乙基)-1-哌嗪乙磺酸（4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID）、5'-单磷酸-5-氟-2'-脱氧尿苷（5-FLUORO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE）、三甘醇（TRIETHYLENE GLYCOL）等。作者：Mathews, I.I.、Deacon, A.M.、Canaves, J.M.、McMullan, D.、Lesley, S.A.、Agarwalla, S.、Kuhn, P.，联合结构基因组学中心（Joint Center for Structural Genomics, JCSG）。存放日期：2003-02-18；发布日期：2003-06-24；最后修改日期：2023-09-20。实验方法：X射线衍射（X-RAY DIFFRACTION，2.1 Å）。引用文献：《胸苷酸合酶互补蛋白的底物与辅因子复合物结构的功能分析》（Functional Analysis of Substrate and Cofactor Complex Structures of a Thymidylate Synthase-Complementing Protein Structure），第11卷，2003年。