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Divergent Total Synthesis of Taiwaniaquinones A and F and Taiwaniaquinols B and D

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NIAID Data Ecosystem2026-03-07 收录
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A divergent approach was developed toward the total synthesis of taiwaniaquinoids. An advanced intermediate 5a with trans A/B ring junction was concisely assembled by employing a Bi(OTf)3-catalyzed cationic cyclization and a Wolff-type ring contraction as key steps. This common intermediate was readily converted to racemic taiwaniaquinones A and F and taiwaniaquinols B and D, respectively.

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2013-04-19
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