Exosomal miRNAs exert a substantial impact on the process of tumorigenesis and exert effects on the composition and function of the tumor microenvironment. This study aimed to clarify the impact of co
The footprint of the aging stroma in older breast cancer patients. Tumoral masses are not only composed of malignant cells, but also enclose a more or less ample stromal micromilieu, which has been s
Myelodysplastic syndromes (MDS) are a heterogeneous group of myeloid neoplasms with defects in hematopoietic stem/progenitor cells (HSPCs) and possibly the HSPC niche. Here we show that patient-derive
Molecular mechanisms of the cancer cells-carcinoma associated fibroblasts (CAF) interactions growing in vitro conditions as a co-culture. The five canine mammary cancer cell lines were cultured with C