Effect of Fluid Resuscitation on Plasma Cytokines in HS-65BV+VP.

Samples were available for all 11 pigs in each group that survived the initial 24 hours and for all the 9 that survived at 72 hours from the group without fluid resuscitation. Values are mean ± SD showing also the median with interquartile range in brackets as values for several time events were not normally distributed. BR, blood reinfusion; NS, normal saline; IL, interleukin; TNF-α, tumor necrosis factor-α. The data was analyzed using two-way repeated measures ANOVA. There was no overall statistically significant treatment effect. There was a statistically significant time effect for IL-8 (p = 0.008), IL-10 (p≤0.001), and TNF-α (p = 0.008). *p≤0.05 denotes a statistically significant difference between groups at the specified time points. ap≤0.001 denotes a statistically significant difference from baseline using the Holm-Sidak test for multiple comparisons.Effect of Fluid Resuscitation on Plasma Cytokines in HS-65BV+VP.