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SUM159 cells treated with H3B-8800 or DMSO, Cytoplasmic fraction RNA-seq. SUM159 cells treated with H3B-8800 or DMSO, Cytoplasmic fraction RNA-seq

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The objective is to identify splicing changes that occur after spliceosome inhibition in triple-negative breast cancer, specifically in cytoplasmic RNA. Overall design: SUM159 cells treated with H3B-8800 (spliceosome inhibitor) or vehicle (DMSO) for 12 hours in biological duplicate. RNA was isolated from the cytoplasm for downstream processing.

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2020-12-15
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