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yCP beta5-A50V mutant in complex with the epoxyketone inhibitor ONX 0914

NIAID Data Ecosystem2026-05-02 收录

蛋白酶体抑制剂复合物结构

蛋白质突变体配体互作

数据链接：

https://www.rcsb.org/structure/4QZ7 数据链接链接失效反馈

官方服务：

资源简介：

yCP beta5-A50V mutant in complex with the epoxyketone inhibitor ONX 0914

应用场景：

创建时间：

2024-11-27

蛋白酶体抑制剂复合物结构

免疫蛋白酶体亚基结合模式

'Yeast 20S proteasome with human beta5i (1-138; V31M) and human beta6 (97-111; 118-133) in complex with epoxyketone inhibitor 18 Descriptor: CHLORIDE ION, MAGNESIUM ION, Probable proteasome subunit al

Protein Data Bank Japan2024-10-23 更新40

Yeast 20S proteasome beta2-G45A mutant in complex with carfilzomib

蛋白酶体抑制剂复合物结构

基于结构的药物设计

Yeast 20S proteasome beta2-G45A mutant in complex with carfilzomib Descriptor: (2~{S})-~{N}-[(2~{S})-1-[[(3~{R},4~{S})-2,6-dimethyl-2,3-bis(oxidanyl)heptan-4-yl]amino]-1-oxidanylidene-3-phenyl-propan-

Protein Data Bank Japan2024-10-16 更新30

yCP beta5-C52F mutant in complex with the epoxyketone inhibitor ONX 0914

蛋白酶体抑制剂复合物结构

药物靶点突变体结合机制

yCP beta5-C52F mutant in complex with the epoxyketone inhibitor ONX 0914

NIAID Data Ecosystem20

yCP beta5-C63F mutant in complex with the epoxyketone inhibitor ONX 0914

蛋白酶体抑制剂复合物结构

蛋白酶体耐药机制

yCP beta5-C63F mutant in complex with the epoxyketone inhibitor ONX 0914 Descriptor: 1,2,4-trideoxy-4-methyl-2-{[N-(morpholin-4-ylacetyl)-L-alanyl-O-methyl-L-tyrosyl]amino}-1-phenyl-D-xylitol, 2-(N-MO

Protein Data Bank Japan2024-11-27 更新30

Yeast 20S proteasome in complex with PR-957 (epoxide)

蛋白酶体抑制剂复合物结构

小分子结合模式解析

Yeast 20S proteasome in complex with PR-957 (epoxide)

NIAID Data Ecosystem20