Phosphine-Catalyzed Domino Reaction: Highly Stereoselective Synthesis of <i>trans</i>-2,3-Dihydrobenzofurans from Salicyl <i>N</i>-Thiophosphinyl Imines and Allylic Carbonates
收藏NIAID Data Ecosystem2026-03-06 收录
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A novel phosphine-catalyzed domino reaction of salicyl N-thiophosphinyl imines and allylic carbonates was developed. The allylic carbonate, in this reaction, serves as a new kind of 1,1-dipolar synthon. This method offered a powerful approach to the construction of a highly substituted trans-2,3-dihydrobenzofuran skeleton with high diastereoselectivity.
创建时间:
2010-09-03



