Crystal Structure of human cyclic GMP-AMP synthase in complex with 2-[(4-phenylphenyl)methylamino]-5-propyl-4H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one:2,2,2-trifluoroacetic acid

Crystal Structure of human cyclic GMP-AMP synthase in complex with 2-[(4-phenylphenyl)methylamino]-5-propyl-4H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one:2,2,2-trifluoroacetic acid Descriptor: (8R)-2-{[([1,1'-biphenyl]-4-yl)methyl]amino}-5-propyl[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one, Cyclic GMP-AMP synthase, ZINC ION Authors: Leibrock, L, Benz, J, Groebke-Zbinden, K, Rudolph, M.G. Deposit date: 2023-02-08 Release date: 2024-02-21 Last modified: 2026-02-18 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Crystal Structure of a human cyclic GMP-AMP synthase complex To be published

人环状GMP-AMP合酶（cyclic GMP-AMP synthase）与2-[(4-苯基苯基)甲氨基]-5-丙基-4H-[1,2,4]三唑并[1,5-a]嘧啶-7-酮:2,2,2-三氟乙酸复合物的晶体结构
描述符：(8R)-2-{[([1,1'-联苯]-4-基)甲基]氨基}-5-丙基[1,2,4]三唑并[1,5-a]嘧啶-7(4H)-酮、环状GMP-AMP合酶、锌离子（ZINC ION）
作者：Leibrock, L、Benz, J、Groebke-Zbinden, K、Rudolph, M.G.
提交日期：2023-02-08
发布日期：2024-02-21
最后修改日期：2026-02-18
实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率2.3埃（Å）
引用文献：《人环状GMP-AMP合酶复合物的晶体结构》，待发表