Mammalian hibernation presents a unique opportunity to study naturally occurring neuroprotection. Hibernating ground squirrels undergo rapid and extreme physiological changes in body temperature, oxyg
Abstract Aim: The preventive and therapeutic role of physical exercise in Parkinson’s disease (PD) has been the target of study of many scientific groups, and the research often is done in experimen
These findings suggest that targeting PGC-1α may be an effective therapeutic strategy for CIRI by regulating mitochondrial homeostasis and protecting neurons from ferroptotic injury.
Celastrol plays a significant role in cerebral ischemia-reperfusion injury. Although previous studies have confirmed that celastrol post-treatment has a protective effect on ischemic stroke, the thera
