SYMPHONEY results_ppmi

SYMPHONY is a clinic-oriented digital twin application designed for structured exploration of longitudinal neurological data. The system provides deterministic clinical risk computation, progression visualization, and formalized report export within a governed browser-based environment. It is implemented as a modular React application with a supporting Node-based server layer responsible for authentication scaffolding, security hardening, and electronic health record (EHR) connectivity abstraction. The current implementation supports structured ingestion of patient data, deterministic transformation through validated numerical utilities, interactive visualization of trajectories, and client-side generation of formal PDF reports. The system is designed to preserve source data integrity and to ensure that computed outputs are reproducible, testable, and version controlled. The intended use is structured clinical reasoning and reporting within a controlled environment suitable for research demonstration, methodological validation, and institutional review.SYMPHONY是一款面向临床场景的数字孪生（digital twin）应用，专为纵向神经学数据的结构化探索而设计。该系统在受管控的浏览器运行环境中，提供确定性临床风险计算、病情进展可视化以及标准化报告导出功能。本项目采用模块化React应用架构，配套基于Node的服务端层，该层负责实现身份验证框架、安全加固以及电子健康记录（Electronic Health Record, EHR）连接抽象。 当前版本支持患者数据的结构化摄入、经验证数值工具完成的确定性转换、病程轨迹的交互式可视化，以及客户端侧的标准化PDF报告生成。该系统旨在保障源数据的完整性，同时确保计算输出具备可复现性、可测试性与版本管控能力。 本系统的预设用途为在适用于研究演示、方法学验证以及机构审查的受控环境中，开展结构化临床推理与报告工作。