BIOGRID CURATED DATA FOR VPS-52 (Caenorhabditis elegans)

Protein-Protein, Genetic, and Chemical Interactions for VPS-52 (Caenorhabditis elegans) curated by BioGRID (https://thebiogrid.org); DEFINITION: vps-52 encodes the C. elegans ortholog of the yeast Vps52p GARP (Golgi associated retrograde protein) complex subunit; in C. elegans, VPS-52 forms a GARP complex with VPS-51, VPS-53, and VPS-54; vps-52 is ubiquitously expressed, with particularly strong expression seen in neurons; a VPS-52::GFP fusion protein localizes to the medial Golgi and trans-Golgi network; VPS-52 physically interacts with the RAB-6.1 and RAB-6.2 Golgi-associated GTPases in vivo.

VPS-52（秀丽隐杆线虫）的蛋白质-蛋白质、遗传和化学相互作用数据集，由BioGRID（https://thebiogrid.org）编纂；定义：vps-52编码秀丽隐杆线虫中酵母Vps52p GARP（高尔基相关逆行蛋白）复合体亚基的同源物；在秀丽隐杆线虫中，VPS-52与VPS-51、VPS-53和VPS-54共同组成GARP复合体；vps-52在体内广泛表达，尤其在神经元中表达强烈；VPS-52::GFP融合蛋白定位于中高尔基体和转高尔基网络；VPS-52在体内与RAB-6.1和RAB-6.2高尔基相关GTPases发生物理相互作用。