E-7386 IS NOT A SPECIFIC CBP/β-CATENIN ANTAGONIST. E-7386 IS NOT A SPECIFIC CBP/β-CATENIN ANTAGONIST
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA916220
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Our data show that E-7386 which has been reported to be a “first-in-class orally active CBP/beta-catenin modulator” anticancer agent, unfortunately by multiple criteria does not appear to be a bona fide CBP/β-catenin selective Overall design: Comparative gene expression profiling analysis of RNA-seq data for SW480 treated with different CBP/β-catenin antagonists (ICG-001, C82, and E7386).
创建时间:
2022-12-27



