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Integrated DNA methylation and DNA hydroxymethylation define epigenetic of etiology dilated cardiomyopathy
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创建时间：
2019-02-10
相关数据集
Methylation status of the ABCG1 , GALNT2 and HMGCR genes promoter in the CHD cases and Non-CHD controls according to subgroup analysis by total samples and gender.
OR: odds ratio; CI: confidence interval; P-value: probability from the Pearson Chi-Square exact test comparing the methylation status for CHD. Cases and Non-CHD controls; P-value*: adjusted for age, g
NIAID Data Ecosystem70
Genome-wide chromatin state in non-failing and dilated cardiomyaphty human left ventricles [ChIP-Seq]. Genome-wide chromatin state in non-failing and dilated cardiomyaphty human left ventricles [ChIP-Seq]
We conducted chromatin immunoprecipitation followed by sequencing (ChIP-seq) and proximity ligation-assisted ChIP-seq (PLAC-seq) for enhancers and promoters (E-P) using left ventricular tissues from d
NIAID Data Ecosystem60
Parallel profiling of DNA methylation and hydroxymethylation highlights neuropathology-associated epigenetic variation in Alzheimer's disease.
Background Alzheimer’s disease is a progressive neurodegenerative disorder that is hypothesized to involve epigenetic dysfunction. Previous studies of DNA modifications in Alzheimer’s disease have bee
NIAID Data Ecosystem30
Selective Class IIa HDAC inhibitor alters gene expression in NRVMs
Expression profiling of neonatl rat ventricular cardiomyocytes (NRVMs) upon the treatement of Class IIa HDAC inhibitor NRVMs were treated with 3 μM TMP195 or DMSO for 48 hours, two sets for each treat
NIAID Data Ecosystem60
Genome-wide chromatin accessibility profiling of cardiomyocyte differentiation from human ES cells and iPS cells under exposure to sublethal of isotretinoin (ATAC-seq). Homo sapiens
In this study, isotretinoin (INN)-induced alternations in genome-wide open-chromatin regions during cardiomyocyte differentiation were investigated. H1-hESC and C15-hiPSC were differentiated to caidio
NIAID Data Ecosystem40
