Hydroxyalkylation-Initiated Radical Cyclization of N‑Allylbenzamide for Direct Construction of Isoquinolinone
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资源简介：
A metal-free hydroxyalkylation-initiated radical six-membered heterocycle formation reaction of N-allylbenzamide is developed. This reaction proceeds through C(sp3)–H bond cleavage, oxyalkylation of the double bond, and intramolecular cyclization, which provides a new route toward 4-substituted 3,4-dihydroisoquinolin-1(2H)-one derivatives.
创建时间：
2016-02-13
