Quercetin attenuates atherosclerosis via modulating oxidized LDL-induced endothelial cellular senescence
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE139288
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We have employed transcriptome microarray expression profiling as a discovery platform to figure out the pharmacological mechanisms of quercetin against endothelial senescence induced by ox-LDL in vitro. Expression of RCHY1, EIF4E1B, IGFBP3, SERPINE1, BRAF, SLC5A11 from this signature was quantified in the same kind of samples by real-time PCR, confirming the change pattern. Human aortic endothelial cells (HAECs) treated with 50 μg/mL ox-LDL with/without 3 μmol/L quercetin were analysed.
创建时间：
2019-10-31
