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A Nonpeptidic Reverse-Turn Scaffold Stabilized by Urea-Based Dual Intramolecular Hydrogen Bonding

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https://figshare.com/articles/dataset/A_Nonpeptidic_Reverse_Turn_Scaffold_Stabilized_by_Urea_Based_Dual_Intramolecular_Hydrogen_Bonding/2635744
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资源简介:
A novel nonpeptidic reverse-turn scaffold containing urea fragments that are connected by a conformationally constrained d-prolyl-cis-1,2-diaminocyclohexane (d-Pro-DACH) linker is reported. The scaffold adopts a well-defined reverse-turn conformation that is stabilized by dual intramolecular hydrogen bonding in both solution and solid states.
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2011-07-01
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