The structure of the FERM domain and helical linker of human moesin bound to a CD44 peptide
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The structure of the FERM domain and helical linker of human moesin bound to a CD44 peptide Descriptor: CD44 antigen, Moesin Authors: Bradshaw, W.J, Katis, V.L, Kelly, J.J, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. Deposit date: 2020-01-14 Release date: 2020-01-29 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Discovery of FERM domain protein-protein interaction inhibitors for MSN and CD44 as a potential therapeutic approach for Alzheimer's disease. J.Biol.Chem., 299, 2023
与CD44肽段结合的人类膜突蛋白(moesin)的FERM结构域(FERM domain)与螺旋连接区结构
描述项:CD44抗原、膜突蛋白(Moesin)
作者:Bradshaw W.J.、Katis V.L.、Kelly J.J.、von Delft F.、Arrowsmith C.H.、Edwards A.、Bountra C.、Gileadi O.
提交日期:2020-01-14
发布日期:2020-01-29
最后修改日期:2024-02-14
实验方法:X射线衍射(分辨率2.2埃)
引用文献:《靶向MSN与CD44的FERM结构域蛋白相互作用抑制剂的发现:阿尔茨海默病潜在治疗途径》,J. Biol. Chem., 299, 2023
创建时间:
2020-01-14



