Additional file 10: Table S5. of Genome-wide transcriptome profiling reveals functional networks involving the Plasmodium falciparum drug resistance transporters PfCRT and PfMDR1

Assessment of a possible time shift in gene expression between parasite lines. We examined the data to assess whether some genes displayed a shifted timing of expression between parasite strains. By comparing peaks of expression for each gene in each pairwise comparison, we determined the number of genes whose peak of expression was shifted of a determined number of hours. 0 corresponds to a shift of less than 1 h, one corresponds to a shift of at least 1 h but less than two hours, etc. Therefore, two genes cannot be more than 24 h apart of each other in either direction. We observed that more than 70 % of all genes peaked within the same 8-hour window in the pfmdr1 dataset (Table S5A) while about 80 % of the genes peaked within the same 5-hour window in the pfcrt dataset (Table S5B). (XLSX 44 kb)