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Reorganization of enhancer patterns in transition from naïve to primed pluripotency

ChEBI2014-06-05 更新2026-07-21 收录

干细胞状态转换

增强子表观遗传学

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-56138 数据链接链接失效反馈

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Reorganization of enhancer patterns in transition from naïve to primed pluripotency

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创建时间：

2014-06-05

干细胞状态转换

2C样状态调控

Mouse embryonic stem cells (mESCs) are not homogenous; a rare subpopulation of cells can sporadically transit into a early-embryonic-like state and exhibits a gene expression program resembling that o

NIAID Data Ecosystem60

Transcriptional profiling of 5iLAF hPSCs (primed to naive converted hPSCs).. Homo sapiens

干细胞转录组学

干细胞状态转换

Transcriptional profiling of 5iLAF hPSCs (primed to naive converted hPSCs).

NIAID Data Ecosystem30

DBC1 is a positive regulator of enhancer epigenomic writers KMT2D and p300 [ChIP-Seq]

增强子表观遗传学

组蛋白修饰ChIP-seq

Genome-wide maps of H3K4me3, H3K4me1, H3K27ac, H3K9/K14ac, and H3K4ac in SW480 WT and DBC1 KO cells Overall design: To identify DBC1-regulated histone H3 modifications, we perfomed ChIP-seq analyses o

NIAID Data Ecosystem20

ELL3 promotes stem cell native to primed transition through LINE-based enhancers [ATAC-seq]

干细胞状态转换

LINE-1增强子调控

Long interspersed nuclear elements-1 (LINE-1) are the clade of retrotransposons still possessing autonomous mobility in mammals. LINE-1 transcription contributed to global chromatin opening in mouse e

NIAID Data Ecosystem40

Cell cycle heterogeneity directs spontaneous 2C state entry and exit in mouse embryonic stem cells (ChIP-Seq). Cell cycle heterogeneity directs spontaneous 2C state entry and exit in mouse embryonic stem cells (ChIP-Seq)

干细胞状态转换

表观遗传调控

Mouse embryonic stem cells (ESCs) show cell-to-cell heterogeneity. A small fraction of 2-cell-like cells (2CLCs) marked by endogenous retrovirus activation emerge spontaneously. The 2CLCs are instable

NIAID Data Ecosystem20

Reorganization of enhancer patterns in transition from naïve to primed pluripotency

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